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References External links Category:Autodesk Category:Computer-related introductions in 1983 Category:Dynamically linked libraries Category:Drawing software Category:3D graphics software Category:Microsoft Windows graphics-related software Category:Technical communication toolsA gene involved in cell death has been found to have a reduced copy number in the cerebellum of patients with autism spectrum disorders, according to a study by a team of researchers at the University of Colorado at Boulder and the University of Texas at Austin. The finding contradicts previous studies that suggest autism occurs due to a rare genetic mutation in the gene. “This is the first study to find a genetic alteration in the cells of patients with autism,” said lead author Dr. Guohua Liu, assistant professor in the departments of psychiatry and neurology at CU-Boulder. “It’s clear the copy number variation in a specific gene is linked to autism, but exactly how is a question for future research.” An estimated 1 in 68 American children is diagnosed with an autism spectrum disorder, according to the Centers for Disease Control and Prevention. Autism spectrum disorder is a group of neurodevelopmental disorders characterized by impairments in social interaction and communication and the presence of restricted, repetitive, and stereotyped behaviors. “The copy number variation (CNV) was identified in a large family with four siblings with autism,” said co-author, Dr. Ian Williams, professor in the Department of Radiology at CU-Boulder. “The CNV in the gene LPPF was shared by all of the children.” Because autism is not heritable, there is no known cause of autism. There is also no known environmental risk factor. The team looked for CNVs, which are common genetic variations, that are copy number variations and are either gain or loss of copy numbers of part of a chromosome. CNVs can be inherited or they can be sporadic, or spontaneous, in nature. According to a recent study published in Science magazine, there are many genes in the brain that could be involved in a child’s development into autism. A complete understanding of the causes of autism requires further study of the brain and its development, especially in children with autism. LPPF encodes a protein found in the synapse called the synaptic cell adhesion molecule (SynCAM1). Genetic e315de8065
# a * acceptance of work, Fitting the Form to an Existing Drawings * ACL, Loading the Autodesk Data Transfer Tool * AEC (as-builts), Reviewing and Modifying Blocks, Creating Drawing Layers, Plan Views and Sections, Defining Materials in the Properties Palette * all faces, Creating a Geometry Array for More Complex Polygons * aliases, Creating a Geometry Array for More Complex Polygons, Creating Your Own Block and Parameter * aligned to, Creating Nested Layers, Fitting the Form to an Existing Drawings * alignment, Alignments * alignment points, Using Alignment Points, Alignment * aligning images, Working with Images, Aligning an Image * Alignments feature, Working with Images, Aligning an Image, Alignment, Using Alignment Points, Alignment * alignments, Using Alignment Points, Alignment, Creating Nested
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Minimum: OS: Windows 7 64-bit (SP1 and later), Windows 8 64-bit (SP1 and later), Windows 8.1 64-bit (SP1 and later) Processor: 1.8 GHz dual-core processor Memory: 1 GB RAM (2 GB recommended) Graphics: DirectX 11 graphics card with 128 MB of video RAM DirectX: Version 11 Storage: 50 MB available space Recommended: OS: Windows 7 64-bit (SP1 and later), Windows 8 64
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